PhD Position in Biomolecular Medicine

Ghent University Department of Biomolecular Medicine

PhD Student

Last application date
Nov 01, 2020 16:27
Department
GE31 - Department of Biomolecular Medicine
Employment category
Doctoral fellow
Contract
Limited duration
Degree
Master in Science (Bioengineering, Biochemistry-Biotechnology, Biomedical Sciences, Medicine)
Occupancy rate
100%
Vacancy Type
Research staff

Job description

The position:

The lab of Translational Onco-genomics and Bioinformatics (supervised by prof. dr. ir. Katleen De Preter) and the lab for Pediatric Oncology (supervised by prof. dr. Frank Speleman and prof. dr. M.D. Bram De Wilde) at the Department of Biomolecular Medicine (UGent) have a vacancy for a highly motivated biomedical researcher with expertise and interest in translational cancer research. More information on the teams and the research focus can be found at www.crig.ugent.be/en/prof-katleen-de-preter-phd and www.crig.ugent.be/en/prof-frank-speleman-phd.

The project:

A new era of clinical care, so-called precision oncology is opening unprecedented potential for developing novel therapeutic strategies for cancer patients. Amongst others, liquid biopsies are now offering a great potential for non-invasive exploration of circulating tumor nucleic acids and cells thus allowing improved diagnostics, tumor follow up, study of heterogeneity, etc. More recently, our teams have implemented several sequencing technologies on liquid biopsies of pediatric cancer patients. The new PhD student will further develop, implement and apply these new tools, finally aiming at an improved clinical management for each individual patient.

The research in our team is supported by several grants focused on DNA and RNA sequencing generated on bulk as well as single cancer cells and nucleic acids obtained using invasive and non-invasive sampling.

Profile of the candidate

Your profile:

  •  You have a Master in Science (Bioengineering, Biochemistry-Biotechnology, Biomedical Sciences, Medicine).
  •  You have knowledge and insight in cancer biology and genomics.
  •  Expertise with laboratory work in a molecular/genetic lab, including DNA- and/or RNA-sequencing technologies, is a plus.
  •  You have, or are willing to be trained in, basic skills in bioinformatics or data mining.
  •  You have analytical problem-solving skills, you are a team player, creative, critical, and open-minded.
  •  You have excellent oral and written communication skills in English.

What we offer:

You will work in a multidisciplinary environment under the supervision of senior scientists in molecular biology and genetics in the Department of Biomolecular Medicine and within the broader framework of the Cancer Research Institute Ghent (crig.ugent.be) where you will perform genomics analysis on pediatric tumors aiming at a more precise care for the patient. We offer:

  • A starting PhD position (including a 6-month evaluation period) after which you will apply for a personal PhD grant with FWO, BOF, etc.,
  • Participation in an exciting and rapidly evolving research area of clinically translational genomics,
  • Being part of a research team operating at international level and dedicated to improving survival of patients with cancer,
  • State-of-the-art technology and facilities (sequencing, single cell sequencing and manipulation, bioinformatics, molecular biology, etc),
  • The opportunity to work in a dynamic and interdisciplinary academic research environment,
  • Embedding within top-research teams with a broad range of expertise,
  • Collaboration with and assistance of wet-lab scientists in the design, analysis and interpretation of cancer genomics data.

How to apply

Candidates can apply by sending their CV and letter of motivation to katleen.depreter@ugent.be before November 1st, 2020. Top-ranked candidates will be invited for an interview (either Zoom/Teams or on site).

Medical Research Building (MRB1)

Department of Biomolecular Medicine

Center for Medical Genetics Ghent (CMGG)

Ghent University Hospital

Corneel Heymanslaan 10

B-9000 Ghent, Belgium

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