02.02.2023, Wissenschaftliches Personal
Within the ‘Chair of Developmental Genetics’, our group combines cutting-edge cell and protein engineering methods for developing novel molecular tools to precisely manipulate the genome and transcriptome of cells and organisms. We apply these tools to various disease models ranging from cell lines and patient-derived stem cells to mouse models. In the past, we used our technologies to treat devasting diseases like Parkinson’s Disease, Duchenne Muscular Dystrophy, or COVID-19 in cellular and animal models. Recently, we developed a synthetic protein to package and transfer RNA into target cell types. With this tool, we were able to express reporter and CRISPR proteins in up to 99% of cells. We now seek to further improve this technology by screening multiple configurations of the transfer protein, by programming target cell types, and by applying the technology to different cellular, ex vivo and in vivo preclinical models.
Your Responsibilities:
Your Scientific Qualifications:
Your Personal Qualifications:
Embedded in the flourishing research environment of two world-class universities, and renowned research institutes in the greater Munich area and equipped with state-of-the-art instruments, the Helmholtz Center Munich - at which our laboratory is located - is an outstanding place for conducting research and for career development. Beyond scientific excellence, Munich offers a wide range of leisure activities ranging from numerous lakes to the close vicinity of the alps.
Salary is in accordance with the collective agreement for the public sector (federal government). The position is initially limited to two years and should begin as soon as possible.
We are looking forward to receiving your application, including a letter of motivation, CV and contact details of at least two references to ‘idg-sekretariat@helmholtz-muenchen.de’. Additionally, we ask you to decide for one of your publications and tell us what it makes so special for you personally.
Curious? Don’t hesitate to contact us for additional information. Join us on our mission toward a new era of precise RNA-based medicines!
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