Post Doc in Pharmacometrics, Pharmacoepidemiology, and Pharmacovigilance

University of Copenhagen Department of Drug Design and Pharmacology

Postdoc in Pharmacometrics, Pharmacoepidemiology, and Pharmacovigilanceat the Department of Drug Design and Pharmacology

Faculty of Health and Medical Sciences
University of Copenhagen

We have a 6 months position available as a postdoc working on the project entitled “Pharmacometrics-based clustering for Pharmacoepidemiological risk stratification in real-world evidence for drugs with a narrow therapeutic index: a data science approach” funded by Helsefonden.

The position is at the University of Copenhagen, within the Department of Drug Design, and Pharmacology and affiliated with the Pharmacovigilance Research Center, but will collaborate with the Pharmacometrics group as the project lies in the interface between the two research fields.

You can find more information about the Pharmacovigilance Research Center and the Pharmacometrics group here:            

  • Pharmacovigilance Research Center: https://drug.ku.dk/disciplines/translational-pharmacology/pharmacovigilance/.
  • Pharmacometrics Research Group: https://drug.ku.dk/disciplines/translational-pharmacology/pharmacometrics/.

The project

This project aims to adapt, integrate and combine pharmacokinetic modelling and simulation, artificial intelligence from data science and epidemiological reasoning from pharmacoepidemiology to improve the quality, efficiency, and cost-effectiveness of drug safety/effectiveness surveillance of drugs with a narrow therapeutic index. It will pose the cornerstone for developing new methodologies for the identification of patients’ subgroups at high risk of adverse drug reactions (including therapeutic failure). The project will pose the conceptual foundation for investigating data dimensions not previously explored in pharmacoepidemiology and will represent a unique opportunity for testing the applicability and feasibility of this new research area in real-world scenarios.

The position

We are looking for a highly motivated and dynamic researcher, to commence 1 March 2021 or as soon as possible thereafter.

You will contribute to the development of pharmacokinetic models for predicting plasma concentration based on patients’ characteristics for selected drugs with a narrow therapeutic index. The predicted plasma concentration will be used to predict the prognosis and the hazard for cause-specific hospitalisation in Danish registers. The position will involve interdisciplinary collaborations with pharmacoepidemiologists and pharmacometricians.

We offer:

  • An interesting job with varied tasks in an active and engaging research environment
  • The opportunity to work with population-based data and with world-class researchers
  • The opportunity for professional advancement and development of an independent research profile
  • An employer with a great societal responsibility who plays an important role in the health and welfare of the Danish population

The ideal candidate     

Essential experience and skills:

  • A PhD degree or similar qualifications within medical sciences, pharmaceutical sciences, public health, biostatistics, or related research field
  • Research experience within population pharmacokinetic modelling
  • Experience with using statistical software such NONNEM, R, or SAS
  • Ability to communicate results academically and as popular science to the general public

Desirable experience and skills:

  • Good interpersonal skills and an enterprising, collaborative and innovative mind-set
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken

Personality traits:

  • You should be innovative, take initiative, and be results-oriented
  • Have an interest in topics relevant to the project
  • The successful candidate should be flexible and able to work independently, efficiently and goal-oriented and contribute to an inclusive working environment

Terms of employment     

The employment as postdoc is a full time and fixed-term position for 6 months. Starting date is 1 March 2021 or after agreement.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 34,650 DKK/ approx. 4,650 Euro (April 2020-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of December 11, 2019.

Questions

For further information please contact Assist. Prof. Maurizio Sessa; maurizio.sessa@sund.ku.dk. 

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure     

Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  1. Motivated letter of application (max. one page).
  2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
  3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  4. List of publications.

Application deadline:  15 December 2020, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process          

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 3.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Maurizio Sessa
E-mail: Maurizio.sessa@sund.ku.dk

Info

Application deadline: 15-12-2020
Employment start: 01-03-2021
Working hours: Full time
Department/Location: Department of Drug Design and Pharmacology
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