The lab of Dr Joo-Hyeon Lee (https://www.stemcells.cam.ac.uk/people/pi/lee) at the Wellcome Medical Research Council Cambridge Stem Cell Institute is looking for a Postdoctoral Fellow/Research Associate to work on an innovative, multi-disciplinary, and collaborative project that investigates the mechanism conferring cell fate competency during tissue regeneration and its significance in disease development
The successful candidates will benefit from multi-disciplinary collaborations and highly innovative experimental model systems (e.g. in vivo novel lineage tracing mouse models, ex vivo mouse and patient-derived human lung organoids, single cell multi-omics, high-resolution imaging platforms, biophysical clonal modelling, etc.) enabling functional interrogation of cell fates and states during regeneration and disease initiation (Lee Lab Publications: Lee et al. Cell 2017; Ombrato et al. Nature 2019; Choi et al. Cell Stem Cell 2020; Youk et al. Cell Stem Cell 2020; Yum et al. Nature 2021; Choi et al. Nature Cell Biol. 2021; Jeon et al. EMBO J. 2022).
Candidates should be enthusiastic about collaborative and interdisciplinary research, the use of innovative technologies, productive, and highly motivated to develop as independent scientists. A strong background in development and stem cell biology, as well as expertise in animal models (preferably genetic mouse models) and multi-omics computational analysis, are required for this post. Experience in primary cell cultures, flow cytometry, and CRISPR genome editing would be advantageous. Candidates will work closely with lab members and collaborators to ensure the quality of our work.
The Wellcome - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/).
Appointment at Research Associate level is dependent on having a PhD, an equivalent research doctorate. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once PhD has been awarded.
Fixed-term: The funds for this post are available for 24 months in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.
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Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
The closing date for applications is: 27th August 2023
The interview date for the role is: To be confirmed
Please quote reference PS37813 on your application and in any correspondence about this vacancy.
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