Postdoctoral Position in Molecular Enzymology and Synthetic Biology

Shanghai Jiao Tong University

Laboratory introduction:

Affiliated to the State Key Laboratory of Microbial Metabolism at SJTU, the Laboratory of Molecular Enzymology and Synthetic Biology is committed to analyzing the law of enzyme catalysis and molecular evolution, developing the technology system of enzyme directed evolution, and facilitating innovative application of enzyme in industry, medicine and other fields.


Aged under 35, with education background in biochemistry, chemical biology, analytical chemistry, etc., and have obtained a doctor's degree in three years or is about to obtain a doctor’s degree;

Good writing and communication skills in both Chinese and English, be able to independently carry out research work, and have published high-level papers during doctoral period or in recent three years;

With strong sense of responsibility, passion for scientific research, be able to work under pressure, have good communication skills, teamwork spirit and innovative ability.

Research directions:

1. Use structural biology, family phylogenetic tree analysis, ancestral gene reconstruction and other methods to reveal the evolution law of key enzyme families in nature, and explore the formation mechanism and regulation law of enzyme high-efficiency catalytic function and substrate selectivity;

2. Develop new techniques and methods of enzyme molecular design and directed evolution, such as protein de novo design and high-throughput screening of microfluidic enzyme activity, so as to improve the efficiency of artificial construction and optimization of engineered enzymes;

3. In view of the important practical application needs, conduct research on design and directed evolution of key enzymes to improve the selectivity of enzymes to non natural substrates, catalytic efficiency and environmental adaptability, and promote the application of enzymes in the field of biomedicine.


1. The annual salary shall be 240,000-280,000 yuan. Excellent candidates can apply for the Shanghai Super Postdoctoral Program, which would increase the income to more than 400,000 yuan;

2. Enjoy 5 social insurances and house fund and other related benefits according to university regulations. Children of candidates can enter the school, kindergarten and primary school of SJTU. Candidates can get Shanghai Hukou according to the regulations of Shanghai Municipal Government;

3. Those who have worked for more than 3 years and have made excellent scientific research achievements can be directly employed as a teacher in the University.

Contact Information

Contact person: Prof. Yang

Phone number: 021-34205079

Address: Room 219, Building 3, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai


Division of Human Resources, SJTU

Publication Date: 2020/9/28