Memorial Sloan Kettering Cancer Center (MSK) is one of the world’s premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers.
The Marians laboratory’s long-standing interests have been in the nature of replication fork operations, the mechanisms of replication fork restart, and the results of collisions between the replication fork and transcription complexes and R-loops. Our approach is centered on biochemical reconstitution experiments using purified proteins and specialized templates to model these processes. We have recently shifted our primary focus from using bacterial proteins to using human proteins to develop these in vitro systems. (https://www.mskcc.org/research/ski/labs/kenneth-j-marians)
The laboratory is part of an exceptionally strong group of researchers investigating diverse aspects of genome integrity in the Molecular Biology Program of Memorial Sloan Kettering Cancer Center (https://www.mskcc.org/research-areas/programs-centers/molecular-biology).
Postdoctoral positions are available for appropriately trained, creative individuals who are interested in how human replication acts both as a genome stabilizer and, when corrupted, as a genome destabilizer. Extensive biochemical training is a must. Familiarity with mammalian overexpression systems is a plus.
Please submit an application with the following required documents:
If you have any questions about this opportunity, please reach out to Kenneth Marians at mariansk@mskcc.org and copying Juyoun Hong at hongj6@mskcc.org.
Salary: $55,439 – $74,263