Postdoctoral Research Associate in Protein Bioconjugation and Glycoscience

University of York Department of Chemistry

Postdoctoral Research Associate in Protein Bioconjugation and Glycoscience

Based at:University of York - Heslington Campus
Hours of work:Full-time
Contract status:Fixed term
Salary:32,817 - 40,322 a year
Interview Date:to be confirmed
Posted Date:22/01/2021
Apply by:21/02/2021
Job Reference:9098

Role Description


Applications are invited for a Postdoctoral Research Associate to work on an EPSRC New Horizons study focussed on “Resurrecting ancestral sugars: a molecular archaeology approach to immunotherapy”, led by Dr Martin Fascione, Department of Chemistry, University of York, and Dr Nathalie Signoret, Hull York Medical School, University of York.

The Department of Chemistry is one of the largest and most successful departments at York and we are renowned internationally for our research. As a department, we strive to provide a working environment that allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.

This project focuses on interdisciplinary protein bioconjugation, glycoscience, immunotherapy studies, and is fixed term for a period of 20 months. The post will suit a chemical biologist with essential expertise in protein bioconjugation. You will work in close collaboration with other group members on the project, and the position will involve synthetic chemistry, protein chemistry, protein expression and some molecular biology.


  • To conduct research under the supervision of Dr Martin Fascione and Dr Nathalie Signoret and to contribute to the production of research
  • To assist in the identification and development of potential areas of research and the development of proposals for independent or collaborative research projects   

Where appropriate you will:

  • provide guidance to other staff and students and coordinate the work of small research teams
  • analyse and write up research results and disseminate them through publications, seminar and conference presentation, public engagement and outreach activities
  • assist with undergraduate teaching
  • undertake appropriate organisational and administrative activities connected to the research project and develop and initiate collaborative working internally and externally

Skills, Experience & Qualifications needed

  • A first degree in Chemistry and a PhD in protein bioconjugation or equivalent experience
  • Knowledge of protein bioconjugation and glycoscience and a range of relevant research techniques and methodologies to engage in high quality research
  • Highly developed oral and written communication skills including presenting at conferences and with experience to write up work for publication
  • Ability to design and perform multistep syntheses of complex small molecules and to perform recombinant expression of proteins in E. coli
  • Ability and experience to develop research objectives and carry out individual and collaborative projects, planning and prioritising own work in order to meet deadlines
  • Experience in Molecular cloning, including site directed mutagenesis
  • Highly motivated and professional and collaborative work ethic, committed to high quality research in this area and a willingness to support colleagues and students
  • Ability to work within a team environment and independently using own initiative and with attention to detail
  • Understanding of and commitment to Equality and Diversity

Interview date: to be confirmed

For informal enquiries: please contact Martin Fascione on

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive. 

The University is committed to promoting a diverse and inclusive community  – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

 A place where we can ALL be ourselves #EqualityatYork