Postdoctoral Research Scientist in Pathology and Cell Biology and Neuroscience

Columbia University New York TBI Taub Institute

Posting Details

Job Requisition Number- 00002057

Position Title- Postdoctoral Research Scientist

Department -TBI Taub Institute

Division -Taub Institute

Location -Medical Center

Summary Description

A position for a highly motivated postdoc is available in the Israely Lab at Columbia University’s Irving Medical Center in the city of New York. We are a part of the Department of Pathology & Cell Biology and the Department of Neuroscience (located in the Taub Institute on Alzheimer’s Disease and the Aging Brain). Our research aims to understand how activity leads to functional and structural alterations in neuronal microcircuits which allow for learning and memory. The long lasting storage of information requires activation of local signaling events, recruitment of new protein synthesis, and induction of structural changes which together support changes in synaptic efficacy that can last a lifetime.

The successful candidate will join us in applying advanced optical methods (such as 2-photon microscopy, glutamate uncaging, and calcium imaging) to manipulate and follow activity at single or groups of spines in living neurons ex vivo. We will probe local hippocampal (and other) circuits with light and electrophysiological approaches, employ various biochemical methods and fluorescent reporters, and leverage the power of genetics to test these questions in mouse models of neurodevelopmental disorders and neurodegeneration. By achieving a fundamental understanding of the learning rules in neurons, we hope to also elucidate critical points of dysfunction which impact learning and memory across human cognitive disorders.

Minimum Degree Required
Ph.D. and/or M.D.

Minimum Qualifications
The ideal candidate will hold a PhD (or equivalent) degree, with experience in at least one or more fields of neuroscience, physiology, biochemistry, cell biology, biomedical engineering or similar disciplines. Applicants with backgrounds in related fields (such as physics or computer science) are welcome to apply.

Familiarity with multiphoton imaging, electrophysiology, tissue culture, molecular biology and programming are highly advantageous. The person must be able to work independently, be proactive in solving problems, and be a leader who contributes towards building an exciting scientific environment. Good communication and writing skills are essential.

Ultimately, the successful candidate will be passionate about discovering how the brain works!

Additional Information

Our lab has ongoing collaborations with many outstanding neuroscientists within the Columbia community, including at the Taub institute, the Center for Translational Neuroscience Initiative, and at the Zuckerman Institute for Mind, Brain, and Behavior (of which we are an affiliate lab).

For consideration and more information, qualified applicants should send a brief description of their background, current work, and future research interests, along with a CV and contact details of three references to

RAPS posting date -12/03/2020

EEO Statement
Columbia University is an Equal Opportunity Employer / Disability / Veteran

Quick Link

Supplemental Questions

Required fields are indicated with an asterisk (*).

Documents Needed to Apply

Required Documents

  • Curriculum Vitae
  • Optional Documents
  • Cover Letter