Postdoctoral Researcher in Digital Precision Medicine and Solid Tumor Biology

University of Helsinki

Docent Toni Seppälä’s lab (älä/) at the University of Helsinki and Helsinki University Hospital has an opening for a

Postdoctoral Researcher

in digital precision medicine and solid tumor biology.

The new researcher will play a leading role in launching a large patient-derived organoid initiative establishing and characterizing individual tumor models. A large number of tumors from multiple gastrointestinal cancer types will undergo comprehensive profiling, and the organoids are used to predict clinical treatment response. Predictive and prognostic liquid biopsy -based biomarkers such as circulating tumor DNA are studied in clinically relevant settings, such as a large randomized controlled trial utilizing the translational precision tools in genuine frameworks of care. Large WES, WGS, RNA-seq, ctDNA, tumor microenvironment and drug response datasets are created and integrated with clinical information.

The aim of our research is to facilitate the use of data intensive biomarkers in patient care, and expand our opportunities to provide precision medicine tools to near future clinical service. Our exploratory aim is to improve understanding of the carcinogenesis focusing on biology of hereditary cancer.

We expect doctoral degree in the applicable field of biomedical sciences and proficiency in spoken and written English. Experience in cell culture and genome editing applications, as well as understanding of cancer biomarkers are highly appreciated. Demonstrated ability to process and handle genomics data is desired, and we appreciate familiarity with R and/or Python. Strong publication record and previous supervisory experience are advantages.

We offer collaborative and multidisciplinary environment with immediate connection to clinical practice. Applied Tumor Genomics (ATG) research program and affiliation to iCAN Flagship of the Academy of Finland provide state of the art infrastructure to conduct both wet lab and computational work in our team that includes trainees and permanent technician staff.

The appointment will be for 12 months starting in June 2021 with a possibility to extension. Trial period of 6 months will be applied. Salary will depend upon the applicant's level of skills, knowledge, and abilities, approximately 3400 to 3900€ per month. Individual development plan will be drafted in the beginning of the appointment to ensure career advancement goals and aims for the postdoctoral period.

Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position’ button below. Internal applicants (i.e. current employees of the University of Helsinki) should submit their applications through the SAP HR portal. Applications written in English should include as a single PDF file:
1) a motivation letter
2) a resume/biosketch
3) list of publications
4) names and email addresses of two academic contacts capable of providing a recommendation for the applicant

The due date for the applications is 11.4.2021 but the call may be closed prematurely for right candidate. Review of applications will begin immediately and continue until the position is filled.

For further information please contact Toni Seppälä: toni.seppala (at) If you need support with the recruitment system, please contact recruitment (at)

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Due date

11.04.2021 23:59 EEST