Research Assistant/Associate in Pharmacology

University of Cambridge Department of Pharmacology

Applications are invited for a researcher position in the laboratory of Dr Catherine Lindon at the Department of Pharmacology, University of Cambridge. We are seeking a motivated cell biologist to undertake studies of the mode of action of novel tools for Targeted Protein Degradation (TPD). Small molecule PROTACs harnessing the cellular ubiquitination machinery to destroy targets of clinical importance are at the forefront of a revolution in therapeutic strategies, yet there are still many parameters of the relevant ubiquitination pathways that are not well understood.

This study is a great opportunity to gain experience in a novel and rapidly expanding field and to contribute to important and timely research questions about how PROTACs find and ubiquitinate their targets, and what cellular factors modify the success of TPD strategies. This knowledge will feed into therapeutic strategies of the future. More information about the laboratory is available at: https://www.phar.cam.ac.uk/research/lindon.

The successful applicant should be about to obtain a PhD or have already obtained a PhD, ideally within the last 5 years. Experience in molecular cell biology is required, and experience in ubiquitin research would be preferred. You must be a careful and methodical worker, be able to take responsibility for your work, interact as part of a tightly knit team and be willing to work in a collaborative environment. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction. The role holder will be required to relocate to the Cambridge area (if not already resident there).

Key duties/responsibilities will include: developing research objectives, conducting the research project, writing up research for presentation and publication, continually updating knowledge and understanding in the research field, translating knowledge of advances in the subject area into research activity, managing own research/administrative activities and contributing to supervision of junior researchers in the lab.

The funds to begin in this post are available from approximately 1st May 2023 with flexibility in start date.

Successful candidates who have not yet been awarded their PhD by the appointment date will be appointed as a Research Assistant at Grade 5 (£27,929 - £32,348). Upon the award of the PhD the individual will be promoted to Research Associate, Grade 7 (£34,308 - £42,155).

Fixed-term: Funds for this post are available for 36-months.

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

Applications will be assessed as and when they are submitted. Interviews will take place in late February.

The online application is to include your personal details, names and addresses of referees, as well as your CV, research publications list and cover letter.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries about the position can be made to Dr Catherine Lindon (acl34@cam.ac.uk)

For enquiries about the online application process, please contact the HR team by emailing hr@phar.cam.ac.uk.

Please quote reference PL34963 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Apply online