Research Associate in Biochemistry

University of Cambridge Department of Biochemistry

We wish to recruit a highly motivated and enthusiastic Postdoctoral Research Associate. The post-holder will join a vibrant research group investigating the links between genome instability and neurodegeneration in the Department of Biochemistry, University of Cambridge. An overview of the Khoronenkova group research interests can be found at

DNA damage signalling and repair are crucial in living cells for the maintenance of genome stability. Multiple genome instability disorders are linked with neurodevelopmental and progressive neurodegenerative phenotypes. However, the underlying mechanisms of these defects remain elusive. Our recent findings implicate glial cell dysfunction in driving neuroinflammation and progressive neurodegeneration in the genome instability disorder Ataxia Telangiectasia. This project will focus on identifying novel pathways that contribute to glia-dependent neurotoxicity in Ataxia Telangiectasia and will hopefully pave the way to the development of novel treatment strategies of this devastating disease.

This interdisciplinary project is funded by the Ataxia Telangiectasia Society and will cross boundaries between biochemistry, molecular biology and iPS based modelling of neurodegenerative disease.

The successful candidate should have (or be close to completion) a PhD in Molecular/Cell Biology, Biochemistry or a related field. Previous experience in human stem cell culture and differentiation would be advantageous. You should have a proven record of success in research and evidence of critical thinking.

Fixed-term: The funds for this post are available for 2 years in the first instance.

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For informal enquiries please contact Dr Svetlana Khoronenkova at

Please contact if you have any questions relating to the application process.

Please quote reference PH26505 on your application and in any correspondence about this vacancy.

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