Research Associate in Biology

University of Cambridge

The University of Cambridge wishes to appoint a talented research associate in bioinformatics and computational biology to join a team of clinical, laboratory and computational scientists in the research groups of Prof Patrick Chinnery and Dr Jelle van den Ameele at the Department of Clinical Neurosciences and the MRC Mitochondrial Biology Unit.

The post holder will lead an exciting project aiming to shed light on the fundamental biology of neurodegenerative diseases and mitochondrial dysfunction, by integrating single-cell and short/-long-read sequencing datasets from novel mouse models of mitochondrial disease and clinical samples, with results from functional genomic screens using CRISPR/Perturb-Seq, and innovative chromatin/epigenome profiling approaches.

This provides a unique opportunity to gain access to patient cohorts and clinical data alongside leading genomic technologies in the Cambridge cluster, and to work closely with other bioinformaticians, laboratory and clinical scientists in the University, Wellcome Sanger Institute, and the EMBL-European Bioinformatics Institute. The team publishes high-profile publications including: Cell 2023 PMID36827974; Nature 2022 PMID36198798; Nature Commun 2022 PMID35468895; Nature Genetics 2021 PMID34002094; Nature Medicine 2021 PMID34426706; eLife 2019 PMID31513013; Science 2019 PMID31123110.

Candidates are expected to be independent, highly motivated, and keen to work collaboratively with wet-lab and computational biologists within and outside the research groups, In addition to their own research, there will be opportunities for training and career development, and supervision of junior researchers.

The role will be located within the MRC Mitochondrial Biology Unit housed in the Wellcome Trust/MRC Building on the Cambridge Biomedical Campus, with state-of-the-art facilities available to group members, including computational resources (i.e. access to HPC facilities, a Linux cluster and storage).

The lab and the wider University of Cambridge are committed, in their pursuit of academic and research excellence, to a pro-active and inclusive approach to equality, which supports and encourages all under-represented groups, promotes an inclusive culture, and values diversity. Flexible working and working from home arrangements will be considered. The University particularly encourages women and candidates from Black, Asian and Minority Ethnic backgrounds to apply.

Lab websites:

Fixed-term: The funds for this post are available for 24 months in the first instance, with the possibility of extending beyond this.

Informal enquiries may be made to Dr Jelle van den Ameele:

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date for applications: 10 September 2023 The interview date: To be confirmed

Please ensure that you upload a covering letter, CV and list of publications, in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please quote reference ZE38012 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online