Research Associate in Biomedical Alzheimer

University of Cambridge

We are seeking an enthusiastic and talented post-doctoral statistician or statistical geneticist with an interest in developing and applying statistical methodology to investigate the relationship between genetics and cognition. The post holder will have access to one of the largest international cohorts of participants (up to 100,000 recruited through the NIHR Bioresource for Translational Research in Common and Rare Diseases) who have agreed to participate in medical research aimed at understanding early dementia and new treatment studies.

Funded through a Biomedical Alzheimer's Society Project Grant, this project will provide a unique opportunity to advance the understanding of the early pre-clinical stages of dementia and the development of new therapies, and to identify a group of people with a higher likelihood of developing dementia for natural history studies and early phase treatment trials. The successful candidate will work in the groups of Dr Brian Tom at the MRC Biostatistics Unit and Professor Patrick Chinnery at the Department of Clinical Neurosciences. The post-holder will also contribute to the research done within the Precision Medicine and Complex Phenotype (PREM) Theme of the Unit.

Candidates for this exciting position should have a PhD in statistics, statistical genetics or in a relevant quantitative discipline, with experience in modelling high-dimensional genetic data and linking to clinical phenotypes. Scientific computing and statistical programming skills in R or equivalent statistical programming language are required. The ability to work independently, to interact effectively as part of a multi-disciplinary team, to be well organised and to communicate clearly are essential. A desire to address questions of substantive biomedical and societal importance is essential.

The MRC Biostatistics Unit is one of Europe's leading biostatistics research institutions. Its focus is to deliver new analytical and computational strategies based on sound statistical principles for the challenging tasks facing biomedicine and public health. The Department of Clinical Neurosciences carries out world leading research in understanding the nervous system in health and disease in order to develop new therapies to treat and prevent neurodegeneration and dementias including Parkinson's disease and Alzheimer's disease. They are both situated on the Cambridge Biomedical Campus, one of the world's most vibrant centres of biomedical research, which includes the University of Cambridge's Clinical School, two major hospitals, the MRC Laboratory of Molecular Biology, and the world headquarters of Astra Zeneca.

We are actively seeking to increase diversity among staff, including promoting an equitable representation of men and women. We therefore especially encourage applications from women, from minority ethnic groups and from those with non-standard career paths. Appointment will be made on merit.

Fixed-term: The funds for this post are available until 30 September 2022 in the first instance.

The post is full-time but applications are welcome from those who would like to work flexibly.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries are welcomed and should be directed to: Dr Brian Tom (

Closing date for applications is: 17/01/2021 Interview date: to be confirmed

Please quote reference SL25163 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.