Research Associate in Directed Evolution

Imperial College London Department of Life Sciences

Job summary

A 1-year Research Associate position is available within the new research group of Dr. Tanai Cardona, the Molecular Evolution Lab, at the Department of Life Sciences, Imperial College London. Photosystem II uses the energy of light to generate the very oxidizing power needed to split water into electrons, protons, and molecular oxygen. This is the photochemical process that sustains almost all life on earth through photosynthesis. Photosystem...

Job listing information

  • Reference NAT00722
  • Date posted 28 July 2020
  • Closing date 27 August 2020

Key information about the role

  • Location South Kensington Campus (map)
  • Position type Full time, fixed term
  • Salary £35,477 – £47,579 plus benefits
  • Department Department of Life Sciences
  • Category Researcher / Non Clinical Researcher

Job description

Job summary

A 1-year Research Associate position is available within the new research group of Dr. Tanai Cardona, the Molecular Evolution Lab, at the Department of Life Sciences, Imperial College London.

Photosystem II uses the energy of light to generate the very oxidizing power needed to split water into electrons, protons, and molecular oxygen. This is the photochemical process that sustains almost all life on earth through photosynthesis. Photosystem II is an ancient enzyme that has evolved an amazing array of functional adaptations to power water oxidation under a huge diversity of environments and variable conditions. How water oxidation originated and how Photosystem II changes through time and ecosystems is poorly understood.

Duties and responsibilities

You will apply and develop approaches to express synthetic D1 and other core subunits of Photosystem II with novel or ancestral traits to study the origin, evolution and evolvability of the complex. You will also initiate a long-term adaptive evolution experiment using your designed, and other strains, to test the dynamics of genome change through the duration of the project.

This position is funded through Tanai’s UKRI Future Leaders Fellowship, titled Directed Evolution of Photosystem Chemistry. This position includes a competitive salary and a number of career development opportunities. You will also benefit from the support of a part-time research technician exclusively associated with this research programme.

For additional information please see attached job description.

Essential requirements

You must hold a PhD (or equivalent) in Molecular Biology, Synthetic Biology, Bioengineering, Biotechnology, Genetic Engineering, Microbiology, Biochemistry, or other within a project that involved an advanced level of DNA/genome manipulation in bacteria or other microbial systems.

You must also meet the following criteria:

  • Experience in genetic engineering of Photosystem II core subunits
  • Experience in molecular biology/genetic engineering of cyanobacteria
  • Ability to innovate new protocols and approaches to tackle complex scientific problems
  • Excellent verbal and written communication skills and ability to deal with a range of people

Further information

To apply

Please use the provided link to submit the online application. Provide a cover letter, your CV and a list of publications.

Informal enquires can be made directly to Dr. Tanai Cardona at t.cardona@imperial.ac.uk.

This is a fixed-term position available for up to 12 months based at the South Kensington Campus.

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £35,477 - £38,566 per annum.

Should you have any queries about the application process please contact recruitmenthub@imperial.ac.uk and refer the job reference number.

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research