Research Fellow in Virology

University of Leeds School of Molecular and Cellular Biology

Research Fellow in Virology

Are you an ambitious researcher looking for your next challenge? Do you have an established background in structural biology or molecular virology? Do you want to further your career in one of the UKs leading research intensive Universities?

Our laboratories are part of a thriving research environment within the Faculty of Biological Sciences, which houses over 150 research groups, 15 of which study viruses. We use structural and cell biology techniques to answer important questions about how RNA viruses perform their infection cycles, and in doing so, we hope to develop strategies to prevent virus growth and thus disease.

The project focusses on how viruses enter cells. Enveloped viruses possess external spikes that must be activated through certain biochemical triggers, such as pH, in order to become infectious. Recently, we showed for the first time that potassium ions in endosomal compartments promote infection of bunyaviruses by causing dramatic structural and functional changes to their spikes (doi: 10.1074/jbc.AAC119.007718 and doi.org/10.1371/journal.ppat.1006845). Building on this work, the project will use state-of-the-art cryo-EM techniques to characterise how the biochemical environments encountered by viruses influence spike structure and function.

You should have a PhD (or be close to completion) in structural biology, molecular virology or a closely allied discipline, with experience in cryo-EM, virology and cell culture techniques, as well as an impressive publication record in high ranking journals. You will work alongside a research technician also assigned to this project, and both will have the opportunity to use and gain experience of state-of-the-art research facilities in molecular virology, cryo-EM, crystallography, and cell imaging.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was reawarded a Bronze award in 2017. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN provides more information.

To explore the post further or for any queries you may have, please contact:

, Associate Professor

Tel: +44 (0)113 343 8069, Email: j.n.barr@leeds.ac.uk

Location: Leeds - Main Campus
Faculty/Service: Faculty of Biological Sciences
School/Institute: School of Molecular & Cellular Biology / Astbury Centre for Structural Molecular Biology
Category: Research
Grade: Grade 7
Salary: £33,797 to £40,322 p.a.
Due to funding limitations, it is unlikely an appointment will be made above £36,914
Working Time: 37.5 hour per week
Post Type: Full Time
Contract Type: Fixed Term (36 months)
Release Date: Tuesday 10 November 2020
Closing Date: Thursday 10 December 2020
Reference: FBSAS1031
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