Researcher in Computational Data Analysis

Uppsala University Department of Cell and Molecular Biology

Researcher in Computational Data Analysis

Published: 2021-01-21

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 45,000 students, more than 7,000 employees and a turnover of around SEK 7 billion.

The position is within the research group of Johan Elf at the program of Molecular Systems Biology. The Elf group works across the borders of conventional research disciplines to investigate life at the molecular level. We build physical models of central biological processes and develop different methods to test these models in living cells. Please see http://elflab.icm.uu.se/ for more information about our activities.

Project description: This project is funded by an ERC advanced grant and aims to determine the dynamic high-resolution 3D structure of the bacterial chromosome. This structure will constitute the basis for understanding the spatial aspects of gene regulation and chromosome organization throughout the cell cycle. The project requires methods development on several different fronts and while the preliminary experimental results are promising, they also suggest that we will face a challenging computational data analysis problem.

Work description: The experimental part of the project will generate thousands of time-dependent distance constraints on the chromosome structure, and you will develop methods to derive dynamic polymer conformations that satisfy these constraints. We offer a stimulating interdisciplinary environment where you will work closely with experts in microbiology, microfluidics, biophysics, image analysis, and molecular biology, but you will be free to shape your part of the project within the framework of the scientific goals. This is a full-time research position, but teaching opportunities exist if there is an interest from the successful candidate.

Qualifications required: You should have a PhD in computational physics or within another area that the employer considers to be equivalent. You are disciplined and have solid skills in numerical optimisation, scientific programming, and modelling of dynamic systems. To be considered for the position, you should also have a creative and self-motivated personality and an interest in fundamental science. Since the project requires collaboration with other researchers in the team, your interpersonal skills should be very good and you should communicate unhindered in English.

Additional qualifications: The ideal candidate has experience with polymer physics, image analysis and experimental biophysics.

The application: Your application should include

  • Cover letter (max 1 page).
  • CV including list of publications.
  • Copy of official academic transcripts.
  • Names, e-mail addresses, and telephone numbers for three reference persons. 

Salary: Individual salary.

Starting date: August 1st, 2021 or as otherwise agreed.

Type of employment: Temporary position of 24 months.

Scope of employment: Full time [100 %]

For further information about the position please contact: Johan Elf johan.elf@icm.uu.se +46-18-471 4678 or Irmeli Barkefors, irmeli.barkefors@icm.uu.se, phone +46-18 471 6681.

Please submit your application by February 26th 2021, UFV-PA 2021/69.

Are you considering moving to Sweden to work at Uppsala University? If so, you will find a lot of information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact International Faculty and Staff Services at ifss@uadm.uu.se.

Please do not send offers of recruitment or advertising services.

Submit your application through Uppsala University's recruitment system.

Placement: Department of Cell and Molecular Biology

Type of employment: Full time , Temporary position longer than 6 months

Pay: Individual salary

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Seko Universitetsklubben seko@uadm.uu.se
ST/TCO tco@fackorg.uu.se
Saco-rådet saco@uadm.uu.se

Number of reference: UFV-PA 2021/69

Last application date: 2021-02-26

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