Researcher in Immunology

Date: 2026-03-04
Location: Uppsala, Sweden
Employment type: Special fixed-term employment
Scope: 100% (Full time)
Duration: 12 months
Number of positions: 1
Reference number: UFV-PA 2026/581
Application deadline: 4 June 2026

About the Department

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focusing on cancer, genetic and autoimmune diseases. A fundamental idea at the department is to stimulate translational research and thereby promote closer interactions between medical research and health care.

Research is presently organized in six research programs:

• Cancer Precision Medicine
• Cancer Immunotherapy
• Genomics and Neurobiology
• Molecular Tools and Functional Genomics
• Neuro-Oncology and Neurodegeneration
• Vascular Biology

Departmental activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Uppsala University Hospital. The department has teaching assignments in several education programs, including Master Programs, at the Faculty of Medicine. The department has a yearly turnover of around SEK 550 million, out of which about two thirds derive from external funding. IGP has approximately 400 employees, out of which 100 are PhD-students, and there are in total more than 850 affiliated staff members.

More information:
www.uu.se/en/staff/department/immunology-genetics-and-pathology

Duties

The position focuses on leveraging zebrafish as a model organism to develop and optimize genetic tools through a directed evolution pipeline, with significant therapeutic and industrial applications. Key responsibilities include:

• Conduct independent research on the development and application of a genetic platform in zebrafish to optimize genetic tools for the treatment of diseases
• Design, execute, and analyze experiments involving prime editing, nanobody engineering, and synthetic enhancer development
• Generate and maintain zebrafish transgenic and knock-in lines for library-based screening
• Perform advanced molecular biology, genome editing, and imaging techniques to study cardiovascular phenotypes
• Collaborate closely with the group leader and other team members, contributing to project planning, data interpretation, and manuscript preparation
• Present research findings at lab meetings, national, and international conferences
• Mentor and provide guidance to junior researchers and students in the lab
• Apply for funding in Sweden and internationally

Requirements

• PhD in molecular biology, developmental biology, cardiovascular biology, biotechnology, or a related field (completed before start of position)
• Proven experience in genome editing techniques (e.g., CRISPR/Cas systems, prime editing, knock-in strategies)
• Strong skills in molecular cloning, PCR-based genotyping, and construct design
• Experience with zebrafish or other vertebrate model organisms
• Ability to work independently and collaboratively in a multidisciplinary team
• Excellent communication skills in English (spoken and written)

Additional qualifications

• Publication record in peer-reviewed journals relevant to the position
• Experience with zebrafish microinjection, transgenesis, and husbandry
• Expertise in live imaging, confocal microscopy, FACS, or high-content screening
• Previous work on cardiovascular biology or muscle-related genetic diseases
• Skills in protein engineering, nanobody development, or synthetic biology
• Knowledge of Swedish legislation & ethics, animal welfare, and 3Rs, as well as laboratory animal science for zebrafish (FELASA or equivalent)
• Experience in mentoring students and collaborative projects
• Creative and proactive mindset with enthusiasm for method development and innovation

Employment

The employment is a temporary position of 12 months at 100% scope. Starting date as agreed. Placement: Uppsala.

For further information about the position, please contact:
Thomas Juan – thomas.juan@igp.uu.se

Application

Submit your application via Uppsala University’s recruitment system.
Last application date: 4 June 2026

Do not send offers of recruitment or advertising services.

About Uppsala University

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.

More information:
https://uu.se/om-uu/jobba-hos-oss/